Perry's untimely demise in October 2023 sparked widespread grief and disbelief among fans worldwide. Despite having battled depression and addiction throughout his life, his death at age 54 was unexpected. Reports indicate that Dr. Plasencia was part of an alleged underground network responsible for supplying Perry with ketamine, a drug he was attempting to obtain in greater quantities than what was prescribed for his mental health treatment.

Details from the plea agreement reveal that between September 30 and October 12, 2023, Dr. Plasencia administered the drug to Perry both at his home and in public locations. The documents also indicate that he instructed Perry's assistant on how to administer the drug and sold them additional vials for personal use. Prosecutors believe that Enrick Mark Chavez, another doctor already pleading guilty in connection with the case, shared messages where Dr. Plasencia referred to Perry as a "moron," illustrating the troubling dynamics surrounding the situation. The case highlights ongoing concerns regarding substance misuse and the responsibilities of healthcare professionals in such matters.